Serum Cystatin C Level, Kidney Disease Markers, and Incidence of Age-Related Macular Degeneration
Open Access
- 9 February 2009
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Ophthalmology
- Vol. 127 (2), 193-199
- https://doi.org/10.1001/archophthalmol.2008.551
Abstract
The finding of a relationship of complement factor H Y402H (1277T→C)genotype status to both age-related macular degeneration (AMD) and kidney disease (membranoproliferative glomerulonephritis type II and hemolytic uremic syndrome) has led to speculation that kidney disease might be associated with AMD.1-16Furthermore, many factors associated with chronic kidney disease (CKD) such as oxidative stress, inflammation, and endothelial dysfunction have been hypothesized to have a role in the pathogenesis of AMD.17-24However, there are few and inconsistent epidemiological data about the relationship of CKD to AMD.25-27Keywords
This publication has 56 references indexed in Scilit:
- CKD Increases the Risk of Age-Related Macular DegenerationJournal of the American Society of Nephrology, 2008
- Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypesHuman Molecular Genetics, 2007
- Changes in Select Redox Proteins of the Retinal Pigment Epithelium in Age-related Macular DegenerationAmerican Journal of Ophthalmology, 2007
- Pigment epithelium-derived factor inhibits oxidative stress-induced cell death by activation of extracellular signal-regulated kinases in cultured retinal pigment epithelial cellsLife Sciences, 2006
- An interactive web database of factor H-associated hemolytic uremic syndrome mutations: insights into the structural consequences of disease-associated mutationsHuman Mutation, 2005
- Genomewide Linkage Analysis to Serum Creatinine, GFR, and Creatinine Clearance in a Community-Based PopulationJournal of the American Society of Nephrology, 2004
- Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney diseaseKidney International, 2004
- Age-related maculopathy in a multiracial United States population: The national health and nutrition examination survey IIIOphthalmology, 1999
- The cystatins: Protein inhibitors of cysteine proteinasesFEBS Letters, 1991
- Prediction of Creatinine Clearance from Serum CreatinineNephron, 1976