Lower Extremity Nerve Function in Patients With Lower Extremity Ischemia

Abstract
Lower extremity peripheral arterial disease (PAD) affects 8 million men and women in the United States.1 Previous studies have identified impaired lower extremity nerve function in patients with PAD with severe, limb-threatening ischemia.2,3 However, most patients with PAD do not develop limb-threatening ischemia. Associations between chronic leg ischemia that is not limb threatening and peripheral nerve function are unclear.4