APLASTIC ANEMIA FOLLOWING VARICELLA VACCINE
- 1 August 2009
- journal article
- case report
- Published by Ovid Technologies (Wolters Kluwer Health) in The Pediatric Infectious Disease Journal
- Vol. 28 (8), 746-748
- https://doi.org/10.1097/inf.0b013e31819b6c1f
Abstract
Varicella zoster vaccine is a safe vaccine that is rarely associated with life-threatening complications. We describe an immunocompetent child who developed transient severe aplastic anemia concomitant with a typical clinical and laboratory-proven chickenpox syndrome 3 weeks after immunization. A causative association between the vaccine and the hematologic disease is possible, and pediatricians should be aware of this severe although rare adverse event.Keywords
This publication has 21 references indexed in Scilit:
- Hepatitis B Virus (HBV) and Autoimmune DiseaseClinical Reviews in Allergy & Immunology, 2007
- Decline in Mortality Due to Varicella after Implementation of Varicella Vaccination in the United StatesThe New England Journal of Medicine, 2005
- Lymphocyte subsets in healthy children from birth through 18 years of age: The pediatric AIDS clinical trials group P1009 studyJournal of Allergy and Clinical Immunology, 2003
- A real-time PCR assay for the detection of varicella-zoster virus DNA and differentiation of vaccine, wild-type and control strainsJournal of Virological Methods, 2003
- Postlicensure Safety Surveillance for Varicella VaccineJAMA, 2000
- Autoimmunity and extrahepatic manifestations in hepatitis C virus infectionJournal of Hepatology, 1999
- An interleukin-2 receptor gamma chain mutation with normal thymus morphology.JCI Insight, 1997
- Licensure of Varicella Virus Vaccine, LiveJAMA, 1995
- Defective T cell receptor signaling and CD8+ thymic selection in humans lacking Zap-70 kinaseCell, 1994
- Varicella-associated pancytopeniaEuropean Journal of Pediatrics, 1990