Progress Toward Cancer Data Ecosystems
- 1 May 2018
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in The Cancer Journal
- Vol. 24 (3), 126-130
- https://doi.org/10.1097/ppo.0000000000000318
Abstract
One of the recommendations of the Cancer Moonshot Blue Ribbon Panel report from 2016 was the creation of a national cancer data ecosystem. We review some of the approaches for building cancer data ecosystems and some of the progress that has been made. A data commons is the colocation of data with cloud computing infrastructure and commonly used software services, tools, and applications for managing, integrating, analyzing, and sharing data to create an interoperable resource for the research community. We discuss data commons and their potential role in cancer data ecosystems and, in particular, how multiple data commons can interoperate to form part of the foundation for a cancer data ecosystem.Keywords
This publication has 36 references indexed in Scilit:
- ClinVar: public archive of relationships among sequence variation and human phenotypeNucleic Acids Research, 2013
- The Cancer Genome Atlas Pan-Cancer analysis projectNature Genetics, 2013
- Identifying Personal Genomes by Surname InferenceScience, 2013
- Harnessing cloud computing with Galaxy CloudNature Biotechnology, 2011
- Galaxy CloudMan: delivering cloud compute clustersBMC Bioinformatics, 2010
- AACR-FDA-NCI Cancer Biomarkers Collaborative Consensus Report: Advancing the Use of Biomarkers in Cancer Drug DevelopmentClinical Cancer Research, 2010
- Ethical and Practical Issues Associated with Aggregating DatabasesPLoS Medicine, 2008
- Research Ethics Recommendations for Whole-Genome Research: Consensus StatementPLoS Biology, 2008
- NCI Thesaurus: A semantic model integrating cancer-related clinical and molecular informationJournal of Biomedical Informatics, 2007
- End-to-end arguments in system designACM Transactions on Computer Systems, 1984