Effect of transgene copy number on survival in the G93A SOD1 transgenic mouse model of ALS
- 4 November 2004
- journal article
- research article
- Published by Elsevier BV in Molecular Brain Research
- Vol. 130 (1-2), 7-15
- https://doi.org/10.1016/j.molbrainres.2004.07.002
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- A novel SOD1 gene mutation in a Korean family with amyotrophic lateral sclerosisJournal of the Neurological Sciences, 2003
- Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstreamExperimental Hematology, 2002
- Rats Expressing Human Cytosolic Copper–Zinc Superoxide Dismutase Transgenes with Amyotrophic Lateral Sclerosis: Associated Mutations Develop Motor Neuron DiseaseJournal of Neuroscience, 2001
- Elevated Cortical Extracellular Fluid Glutamate in Transgenic Mice Expressing Human Mutant (G93A) Cu/Zn Superoxide DismutaseJournal of Neurochemistry, 2000
- The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studiesJournal of the Neurological Sciences, 1997
- A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase ( SOD1 ) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosisActa Neuropathologica, 1997
- ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing InclusionsNeuron, 1997
- Age-Dependent Penetrance of Disease in a Transgenic Mouse Model of Familial Amyotrophic Lateral SclerosisMolecular and Cellular Neuroscience, 1995
- Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS)Brain Research, 1995
- Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase MutationScience, 1994