Photoregulated Release of Caged Anticancer Drugs from Gold Nanoparticles
Top Cited Papers
- 7 April 2009
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 131 (16), 5728-5729
- https://doi.org/10.1021/ja900591t
Abstract
An anticancer drug (5-fluorouracil) was conjugated to the surface of gold nanoparticles through a photocleavable o-nitrobenzyl linkage. In this system, the particle serves as both cage and carrier for the therapeutic, providing a nontoxic conjugate that effectively releases the payload upon long wavelength UV irradiation.This publication has 32 references indexed in Scilit:
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