Genomic evaluations with many more genotypes
Top Cited Papers
Open Access
- 2 March 2011
- journal article
- Published by Springer Science and Business Media LLC in Genetics Selection Evolution
- Vol. 43 (1), 10
- https://doi.org/10.1186/1297-9686-43-10
Abstract
Genomic evaluations in Holstein dairy cattle have quickly become more reliable over the last two years in many countries as more animals have been genotyped for 50,000 markers. Evaluations can also include animals genotyped with more or fewer markers using new tools such as the 777,000 or 2,900 marker chips recently introduced for cattle. Gains from more markers can be predicted using simulation, whereas strategies to use fewer markers have been compared using subsets of actual genotypes. The overall cost of selection is reduced by genotyping most animals at less than the highest density and imputing their missing genotypes using haplotypes. Algorithms to combine different densities need to be efficient because numbers of genotyped animals and markers may continue to grow quickly.This publication has 28 references indexed in Scilit:
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