13C-Pyruvate Imaging Reveals Alterations in Glycolysis that Precede c-Myc-Induced Tumor Formation and Regression
Open Access
- 1 July 2011
- journal article
- resource
- Published by Elsevier BV in Cell Metabolism
- Vol. 14 (1), 131-142
- https://doi.org/10.1016/j.cmet.2011.04.012
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Rethinking the Warburg Effect with Myc Micromanaging Glutamine MetabolismCancer Research, 2010
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progressionProceedings of the National Academy of Sciences of the United States of America, 2010
- 3D compressed sensing for highly accelerated hyperpolarized 13C MRSI with in vivo applications to transgenic mouse models of cancerMagnetic Resonance in Medicine, 2009
- Kinetics of hyperpolarized 13 C 1 -pyruvate transport and metabolism in living human breast cancer cellsProceedings of the National Academy of Sciences of the United States of America, 2009
- Understanding the Warburg Effect: The Metabolic Requirements of Cell ProliferationScience, 2009
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addictionProceedings of the National Academy of Sciences of the United States of America, 2008
- Hyperpolarized 13C Lactate, Pyruvate, and Alanine: Noninvasive Biomarkers for Prostate Cancer Detection and GradingCancer Research, 2008
- Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cellsThe Journal of cell biology, 2007
- Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profilesProceedings of the National Academy of Sciences of the United States of America, 2005
- MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancerNature, 2004