The Quality of Tumor Size Assessment by Contrast-Enhanced Spectral Mammography and the Benefit of Additional Breast MRI
- 1 January 2015
- journal article
- Published by Ivyspring International Publisher in Journal of Cancer
- Vol. 6 (2), 144-150
- https://doi.org/10.7150/jca.10705
Abstract
Background - Contrast-enhanced spectral mammography (CESM) is a promising new breast imaging modality that is superior to conventional mammography for breast cancer detection. We aimed to evaluate correlation and agreement of tumor size measurements using CESM. As additional analysis, we evaluated whether measurements using an additional breast MRI exam would yield more accurate results. Methods - Between January 1(st) 2013 and April 1(st) 2014, 87 consecutive breast cancer cases that underwent CESM were collected and data on maximum tumor size measurements were gathered. In 57 cases, tumor size measurements were also available for breast MRI. Histopathological results of the surgical specimen served as gold standard in all cases. Results - The Pearson's correlation coefficients (PCC) of CESM versus histopathology and breast MRI versus histopathology were all >0.9, p1 cm between the two imaging modalities and histopathological results, we did not observe any advantage of performing an additional breast MRI after CESM in any of the cases. Conclusion - Quality of tumor size measurement using CESM is good and matches the quality of these measurement assessed by breast MRI. Additional measurements using breast MRI did not improve the quality of tumor size measurements.Keywords
This publication has 20 references indexed in Scilit:
- Low energy mammogram obtained in contrast-enhanced digital mammography (CEDM) is comparable to routine full-field digital mammography (FFDM)European Journal of Radiology, 2014
- Contrast-Enhanced Digital MammographyRadiologic Clinics of North America, 2014
- Contrast-enhanced spectral mammography in patients referred from the breast cancer screening programmeEuropean Radiology, 2014
- Good correlation does not automatically imply good agreement: The trouble with comparing tumour size by breast MRI versus histopathologyEuropean Journal of Radiology, 2013
- Breast cancer size estimation with MRI in BRCA mutation carriers and other high risk patientsEuropean Journal of Radiology, 2013
- Does breast cancer tumor size really matter that much?The Breast, 2012
- Breast Cancer Tumor Size Assessment with Mammography, Ultrasonography, and Magnetic Resonance Imaging at a Community Based Multidisciplinary Breast CenterThe American Surgeon, 2012
- Contrast-enhanced digital mammographyEuropean Journal of Radiology, 2009
- The effect of tissue fixation and processing on breast cancer sizeHuman Pathology, 2005
- Statistical methods for assessing agreement between two methods of clinical measurement.1986