Enzyme inhibition activities of the extracts from rhizomes ofGloriosa superbaLinn (Colchicaceae)
Open Access
- 1 January 2007
- journal article
- research article
- Published by Taylor & Francis Ltd in Journal of Enzyme Inhibition and Medicinal Chemistry
- Vol. 22 (6), 722-725
- https://doi.org/10.1080/14756360601164853
Abstract
An alcoholic extract obtained from the rhizomes of Gloriosa superba Linn (Colchicaceae) was screened for enzyme inhibition activities. The crude extract and its subsequent fractions including chloroform, ethyl acetate, n-butanol and aqueous were screened against lipoxygenase, actylcholinesterase, butyrylcholinesterase and urease. An outstanding inhibition on lipoxygenase was observed. The highest enzyme inhibition potency was expressed by the chloroform fraction (90%) among the tested fractions on lipoxygenase. Overall 67– 90% inhibition was found for lipoxygenase, 46-69% for acetylcholinesterase and 10–33% for butyrylcholinesterase, while urease was not inhibited.Keywords
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