Up to now computerized interactive 3-dimensional (3D) atlases of human anatomy have been based on radiological data or artificial geometric models as spatial descriptions of morphological structures. Besides the obvious advantages of this data (e.g. already in digital format, geometrical correctness) the lack of high resolution anatomical slices of larger regions of the human body has prevented the use of more realistic anatomical data so far. Now, the Visible Human Project offers high quality anatomical slices of complete cadavers. Therefore, on the one hand, new opportunities for realistic virtual 3D models of anatomy are open. On the other hand, just the major advantages of the visible human data (e.g. realistic colors and textures, high resolution) result in new demands on the image processing and visualization techniques. This paper describes experience, solutions and results with a volume-based approach for building realistic anatomical 3D models.