Optimal clinical management of children receiving the ketogenic diet: Recommendations of the International Ketogenic Diet Study Group
- 27 January 2009
- Vol. 50 (2), 304-317
- https://doi.org/10.1111/j.1528-1167.2008.01765.x
Abstract
The ketogenic diet (KD) is an established, effective nonpharmacologic treatment for intractable childhood epilepsy. The KD is provided differently throughout the world, with occasionally significant variations in its administration. There exists a need for more standardized protocols and management recommendations for clinical and research use. In December 2006, The Charlie Foundation commissioned a panel comprised of 26 pediatric epileptologists and dietitians from nine countries with particular expertise using the KD. This group was created in order to create a consensus statement regarding the clinical management of the KD. Subsequently endorsed by the Practice Committee of the Child Neurology Society, this resultant manuscript addresses issues such as patient selection, pre-KD counseling and evaluation, specific dietary therapy selection, implementation, supplementation, follow-up management, adverse event monitoring, and eventual KD discontinuation. This paper highlights recommendations based on best evidence, including areas of agreement and controversy, unanswered questions, and future research.Keywords
This publication has 80 references indexed in Scilit:
- When do seizures usually improve with the ketogenic diet?Epilepsia, 2007
- Lack of Influence of Body Mass Index on the Efficacy of the Ketogenic DietJournal of Child Neurology, 2007
- Home-Guided Use of the Ketogenic Diet in a Patient for More Than 20 YearsPediatric Neurology, 2007
- Efficacy and Tolerability of the Ketogenic Diet According to Lipid:Nonlipid Ratios—Comparison of 3:1 with 4:1 DietEpilepsia, 2007
- Long-term use of the ketogenic diet in the treatment of epilepsyDevelopmental Medicine and Child Neurology, 2006
- Ketogenic diet for treatment of infantile spasmsBrain & Development, 2006
- Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic dietBrain & Development, 2006
- Ketogenic diet in pediatric epilepsy patients with gastrostomy feedingPediatric Neurology, 2005
- Ketogenic diet: Outpatient initiation, without fluid, or caloric restrictionsPediatric Neurology, 2004
- Effect of Intraluminal pH on the Absorption of Pteroylmonoglutamic AcidBMJ, 1971