Echocardiography in Mice
Open Access
- 1 March 2011
- journal article
- research article
- Published by Wiley in Current Protocols in Mouse Biology
- Vol. 1 (1), 71-83
- https://doi.org/10.1002/9780470942390.mo100130
Abstract
Murine models have been utilized with increasing frequency mainly due to availability of genetically engineered models. With advancement in high spatial and temporal resolution, echocardiography is used extensively for the evaluation of cardiovascular function in murine models of cardiovascular disease. This review summarizes the general applications and methods involved in echocardiography used to study mouse models for cardiovascular research, based on 20 years of experience in the authors' laboratory. The goal of this article is to provide a practical guide to the use of echo techniques in mice to evaluate cardiac systolic and diastolic function. Curr. Protoc. Mouse Biol. 1:71-83. © 2011 by John Wiley & Sons, Inc.Keywords
This publication has 54 references indexed in Scilit:
- Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overloadAmerican Journal of Physiology-Heart and Circulatory Physiology, 2010
- Genetic inhibition of calcineurin induces diastolic dysfunction in mice with chronic pressure overloadAmerican Journal of Physiology-Heart and Circulatory Physiology, 2009
- Myocardial Alterations in Senescent Mice and Effect of Exercise TrainingCirculation: Cardiovascular Imaging, 2008
- Echocardiography in Translational Research: Of Mice and MenJournal of the American Society of Echocardiography, 2008
- Doppler Estimation of Reduced Coronary Flow Reserve in Mice with Pressure Overload Cardiac HypertrophyJapanese Journal of Clinical Oncology, 2008
- Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnIAmerican Journal of Physiology-Heart and Circulatory Physiology, 2008
- Type 5 Adenylyl Cyclase Disruption Increases Longevity and Protects Against StressCell, 2007
- High-resolution imaging of murine myocardial infarction with delayed-enhancement cine micro-CTAmerican Journal of Physiology-Heart and Circulatory Physiology, 2007
- Inhibition of p38α MAPK rescues cardiomyopathy induced by overexpressed β2-adrenergic receptor, but not β1-adrenergic receptorJCI Insight, 2007
- β-Adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic Gsα mouseJCI Insight, 1999