Three Cases of Acute Hepatitis E Virus Infection Imported into Norway

Abstract
We report 3 cases of acute hepatitis E virus (HEV) infection imported from Asia. All 3 patients had fever and upper abdominal discomfort preceding jaundice which lasted 2–3 weeks with maximum bilirubin levels of 141–254 mmol/l. The ALT values peaked between 1,347 and 3,690 U/l. Both values normalized within 1–2 months. During the acute phase of the disease, all patients had high levels of IgG and IgM antibodies against HEV (anti-HEV) recombinant and synthetic peptides. The duration of the anti-HEV IgM was about 1–2 months.