Simulation of phase contrast MRI of turbulent flow
Open Access
- 22 June 2010
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 64 (4), 1039-1046
- https://doi.org/10.1002/mrm.22494
Abstract
Phase contrast MRI is a powerful tool for the assessment of blood flow. However, especially in the highly complex and turbulent flow that accompanies many cardiovascular diseases, phase contrast MRI may suffer from artifacts. Simulation of phase contrast MRI of turbulent flow could increase our understanding of phase contrast MRI artifacts in turbulent flows and facilitate the development of phase contrast MRI methods for the assessment of turbulent blood flow. We present a method for the simulation of phase contrast MRI measurements of turbulent flow. The method uses an Eulerian‐Lagrangian approach, in which spin particle trajectories are computed from time‐resolved large eddy simulations. The Bloch equations are solved for each spin for a frame of reference moving along the spins trajectory. The method was validated by comparison with phase contrast MRI measurements of velocity and intravoxel velocity standard deviation (IVSD) on a flow phantom consisting of a straight rigid pipe with a stenosis. Turbulence related artifacts, such as signal drop and ghosting, could be recognized in the measurements as well as in the simulations. The velocity and the IVSD obtained from the magnitude of the phase contrast MRI simulations agreed well with the measurements. Magn Reson Med, 2010.This publication has 27 references indexed in Scilit:
- Quantifying Turbulent Wall Shear Stress in a Stenosed Pipe Using Large Eddy SimulationJournal of Biomechanical Engineering, 2010
- Transit of Blood Flow Through the Human Left Ventricle Mapped by Cardiovascular Magnetic ResonanceJournal of Cardiovascular Magnetic Resonance, 2007
- Ascending–descending aortic bypass surgery in aortic arch coarctation: Four-dimensional magnetic resonance flow analysisThe Journal of Thoracic and Cardiovascular Surgery, 2007
- ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SCAI/SIR 2006 Appropriateness Criteria for Cardiac Computed Tomography and Cardiac Magnetic Resonance Imaging⁎⁎Developed in accordance with the principles and methodology outlined by ACCF: Patel MR, Spertus JA, Brindis RG, Hendel RC, Douglas PS, Peterson ED, Wolk MJ, Allen JM, Raskin IE. ACCF proposed method for evaluating the appropriateness of cardiovascular imaging. J Am Coll Cardiol 2005;46:1606–13.Journal of the American College of Cardiology, 2006
- Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report?European Heart Journal, 2004
- Flow patterns in the aortic root and the aorta studied with time-resolved, 3-dimensional, phase-contrast magnetic resonance imaging: implications for aortic valve–sparing surgeryThe Journal of Thoracic and Cardiovascular Surgery, 2004
- Time-Resolved 3-Dimensional Velocity Mapping in the Thoracic AortaJournal of Computer Assisted Tomography, 2004
- Asymmetric redirection of flow through the heartNature, 2000
- Temporally resolved 3D phase‐contrast imagingMagnetic Resonance in Medicine, 1996
- Calculation of the magnetization distribution for fluid flow in curved vesselsMagnetic Resonance in Medicine, 1996