Taking the time to make important decisions: The checkpoint effector kinases Chk1 and Chk2 and the DNA damage response
- 2 September 2009
- journal article
- review article
- Published by Elsevier BV in DNA Repair
- Vol. 8 (9), 1047-1054
- https://doi.org/10.1016/j.dnarep.2009.04.012
Abstract
No abstract availableKeywords
This publication has 99 references indexed in Scilit:
- Specific Role of Chk1 Phosphorylations in Cell Survival and Checkpoint ActivationMolecular and Cellular Biology, 2007
- Mechanism of Dun1 Activation by Rad53 Phosphorylation in Saccharomyces cerevisiaePublished by Elsevier BV ,2007
- Role for the PP2A/B56δ Phosphatase in Regulating 14-3-3 Release from Cdc25 to Control MitosisCell, 2006
- Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATRThe Journal of cell biology, 2006
- Differential Roles of ATM- and Chk2-Mediated Phosphorylations of Hdmx in Response to DNA DamageMolecular and Cellular Biology, 2006
- ATM–Chk2–p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiencyThe EMBO Journal, 2006
- Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeastGenes & Development, 2006
- ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damageThe EMBO Journal, 2005
- Activation of the DNA damage checkpoint and genomic instability in human precancerous lesionsNature, 2005
- DNA damage response as a candidate anti-cancer barrier in early human tumorigenesisNature, 2005