Growth and aging: a common molecular mechanism
Open Access
- 20 April 2009
- journal article
- review article
- Published by Impact Journals, LLC in Aging
- Vol. 1 (4), 357-362
- https://doi.org/10.18632/aging.100040
Abstract
It is commonly assumed that growth and aging are somehow linked, but the nature of this link has been elusive. Here we review the aging process as a continuation of TOR-driven growth. TOR is absolutely essential for developmental growth, but upon completion of development it causes aging and age-related diseases. Thus, the nutrient-sensing and growth-promoting TOR signaling pathway may provide a molecular link between growth and aging that is universal from yeast to human.Keywords
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