Mutation in the Heparan Sulfate Biosynthesis Enzyme EXT1 Influences Growth Factor Signaling and Fibroblast Interactions with the Extracellular Matrix
Open Access
- 1 December 2009
- journal article
- Published by Elsevier BV
- Vol. 284 (50), 34935-34943
- https://doi.org/10.1074/jbc.m109.005264
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- Evidence That Heparin Saccharides Promote FGF2 Mitogenesis through Two Distinct MechanismsJournal of Biological Chemistry, 2008
- Specific Heparan Sulfate Structures Modulate FGF10-mediated Submandibular Gland Epithelial Morphogenesis and DifferentiationJournal of Biological Chemistry, 2008
- Heparan sulfate–dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblastsArthritis & Rheumatism, 2008
- Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathwaysExperimental Cell Research, 2007
- α11β1 Integrin-Dependent Regulation of Periodontal Ligament Function in the Erupting Mouse IncisorMolecular and Cellular Biology, 2007
- Heparan sulphate proteoglycans fine-tune mammalian physiologyNature, 2007
- Cellular Adhesion Responses to the Heparin-binding (HepII) Domain of Fibronectin Require Heparan Sulfate with Specific PropertiesJournal of Biological Chemistry, 2007
- Heparan Sulfate: A Complex Polymer Charged with Biological ActivityChemical Reviews, 2005
- Embryonic Fibroblasts with a Gene Trap Mutation in Ext1 Produce Short Heparan Sulfate ChainsPublished by Elsevier BV ,2004
- In Vitro Polymerization of Heparan Sulfate Backbone by the EXT ProteinsJournal of Biological Chemistry, 2003