Near‐haploid karyotype in a squamous cell lung carcinoma
- 1 August 1993
- journal article
- research article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 7 (4), 209-212
- https://doi.org/10.1002/gcc.2870070405
Abstract
Cytogenetic analysis of a squamous cell lung carcinoma revealed a near-haploid karyotype with 27 chromosomes, in both primary cultures and an established cell line. The only chromosomes with two homologs present were chromosomes X, 5, 7, and 22. The two X chromosomes were early and late replicating, respectively. No structural rearrangements could be detected. In vitro, the clone evolved by duplication towards hyperdiploidy with 54 chromosomes.Keywords
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