Hyperalgesia Induced by Naloxone Follows Diurnal Rhythm in Responsivity to Painful Stimuli
- 18 November 1977
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 198 (4318), 756-758
- https://doi.org/10.1126/science.561998
Abstract
A diurnal rhythm was observed in the responsiveness of mice to nociceptive stimuli and in the hyperalgesic activity of endogenous opioid peptides and may partly account for previous controversy over the direct action of naloxone in opiate-naive animals.This publication has 23 references indexed in Scilit:
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