Factors Underlying Ebola Virus Infection Among Health Workers, Kenema, Sierra Leone, 2014–2015
Open Access
- 18 May 2016
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 63 (4), 454-459
- https://doi.org/10.1093/cid/ciw327
Abstract
Background. Ebola virus disease (EVD) in health workers (HWs) has been a major challenge during the 2014–2015 outbreak. We examined factors associated with Ebola virus exposure and mortality in HWs in Kenema District, Sierra Leone. Methods. We analyzed data from the Sierra Leone National Viral Hemorrhagic Fever Database, contact tracing records, Kenema Government Hospital (KGH) staff and Ebola Treatment Unit (ETU) rosters, and burial logs. Results. From May 2014 through January 2015, 600 cases of EVD originated in Kenema District, including 92 (15%) HWs, 66 (72%) of whom worked at KGH. Among KGH medical staff and international volunteers, 18 of 62 (29%) who worked in the ETU developed EVD, compared with 48 of 83 (58%) who worked elsewhere in the hospital. Thirteen percent of HWs with EVD reported contact with EVD patients, while 27% reported contact with other infected HWs. The number of HW EVD cases at KGH declined roughly 1 month after implementation of a new triage system at KGH and the opening of a second ETU within the district. The case fatality ratio for HWs and non-HWs with EVD was 69% and 74%, respectively. Conclusions. The cluster of HW EVD cases in Kenema District is one of the largest ever reported. Most HWs with EVD had potential virus exposure both inside and outside of hospitals. Prevention measures for HWs must address a spectrum of infection risks in both formal and informal care settings as well as in the community.This publication has 29 references indexed in Scilit:
- A tribute to Sheik Humarr Khan and all the healthcare workers in West Africa who have sacrificed in the fight against Ebola virus disease: Mae we hushAntiviral Research, 2014
- Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learnedBMC Infectious Diseases, 2011
- The 1995 Kikwit Ebola outbreak: lessons hospitals and physicians can apply to future viral epidemicsGeneral Hospital Psychiatry, 2008
- New opportunities for field research on the pathogenesis and treatment of Lassa feverAntiviral Research, 2008
- On the Front Lines of Lassa FeverEmerging Infectious Diseases, 2004
- The Reemergence of Ebola Hemorrhagic Fever, Democratic Republic of the Congo, 1995The Journal of Infectious Diseases, 1999
- Ebola Outbreak in Kikwit, Democratic Republic of the Congo: Discovery and Control MeasuresThe Journal of Infectious Diseases, 1999
- Organization of Patient Care during the Ebola Hemorrhagic Fever Epidemic in Kikwit, Democratic Republic of the Congo, 1995The Journal of Infectious Diseases, 1999
- A Prospective Study of the Epidemiology and Ecology of Lassa FeverThe Journal of Infectious Diseases, 1987
- Effect of environmental factors on aerosol‐induced lassa virus infectionJournal of Medical Virology, 1984