Apolipoprotein E3 (ApoE3) but Not ApoE4 Protects against Synaptic Loss through Increased Expression of Protein Kinase Cϵ
Open Access
- 1 May 2012
- journal article
- Published by Elsevier BV
- Vol. 287 (19), 15947-15958
- https://doi.org/10.1074/jbc.m111.312710
Abstract
No abstract availableThis publication has 63 references indexed in Scilit:
- Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal TraffickingPLOS ONE, 2010
- Overexpression of Low-Density Lipoprotein Receptor in the Brain Markedly Inhibits Amyloid Deposition and Increases Extracellular Aβ ClearanceNeuron, 2009
- Reduction of β-Amyloid Levels by Novel Protein Kinase Cϵ ActivatorsPublished by Elsevier BV ,2009
- Isolation and Characterization of Patient-derived, Toxic, High Mass Amyloid β-Protein (Aβ) Assembly from Alzheimer Disease BrainsPublished by Elsevier BV ,2009
- Protection of Neurons from Apoptosis by Apolipoprotein E-containing Lipoproteins Does Not Require Lipoprotein Uptake and Involves Activation of Phospholipase Cγ1 and Inhibition of CalcineurinPublished by Elsevier BV ,2009
- The Role of Apolipoprotein E in Alzheimer's DiseaseNeuron, 2009
- Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyNature Reviews Neuroscience, 2009
- ApoE Promotes the Proteolytic Degradation of AβNeuron, 2008
- A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKCProceedings of the National Academy of Sciences of the United States of America, 2007
- Beta-amyloid disrupted synaptic vesicle endocytosis in cultured hippocampal neuronsNeuroscience, 2007