Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis
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Open Access
- 15 February 2021
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 325 (7), 646-657
- https://doi.org/10.1001/jama.2021.0411
Abstract
Osteoarthritis is the most common form of arthritis and a leading cause of disability among adults.1 A report from 2012 estimated that knee osteoarthritis affected more than 250 million people worldwide.2 Clinical guidelines recommend strength training for patients with knee osteoarthritis based on clinical trial evidence of effectiveness.3 Improved strength mediates pain relief,4 enhances psychological well-being,5 maintains cartilage integrity in animal models,6,7 and may increase the shock absorbing capability of lower extremity muscles during walking.8 Limitations of prior randomized trials of strength training for patients with osteoarthritis include the use of training intensities below those recommended by practice guidelines9-13 and use of short-duration interventions, lasting between 6 and 24 weeks.11,12Keywords
This publication has 41 references indexed in Scilit:
- Strength Training for Arthritis Trial (START): design and rationaleBMC Musculoskeletal Disorders, 2013
- Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010The Lancet, 2013
- Weight loss as treatment for knee osteoarthritis symptoms in obese patients: 1-year results from a randomised controlled trialAnnals Of The Rheumatic Diseases, 2011
- Cutpoints for mild, moderate and severe pain in patients with osteoarthritis of the hip or knee ready for joint replacement surgeryBMC Musculoskeletal Disorders, 2008
- Atlas of individual radiographic features in osteoarthritis, revisedOsteoarthritis and Cartilage, 2007
- Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: The arthritis, diet, and activity promotion trialArthritis & Rheumatism, 2004
- The mechanism of the effect of obesity in knee osteoarthritis: The mediating role of malalignmentArthritis & Rheumatism, 2000
- Exercise protects against articular cartilage degeneration in the hamsterArthritis & Rheumatism, 1998
- A Randomized Controlled Trial of Progressive Resistance Training in Depressed EldersThe Journals of Gerontology: Series A, 1997
- The incidence and natural history of knee osteoarthritis in the elderly, the framingham osteoarthritis studyArthritis & Rheumatism, 1995