Paramagnetic Liposome Nanoparticles for Cellular and Tumour Imaging
Open Access
- 14 April 2010
- journal article
- review article
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 11 (4), 1759-1776
- https://doi.org/10.3390/ijms11041759
Abstract
In this review we discuss the development of paramagnetic liposomes incorporating MRI contrast agents and show how these are utilized in cellular imaging in vitro. Bi-functional, bi-modal imaging paramagnetic liposome systems are also described. Next we discuss the upgrading of paramagnetic liposomes into bi-modal imaging neutral nanoparticles for in vivo imaging applications. We discuss the development of such systems and show how paramagnetic liposomes and imaging nanoparticles could be developed as platforms for future multi-functional, multi-modal imaging theranostic nanodevices tailor-made for the combined imaging of early stage disease pathology and functional drug delivery.Keywords
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