Alterations in Smell or Taste in Mildly Symptomatic Outpatients With SARS-CoV-2 Infection
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Open Access
- 26 May 2020
- journal article
- letter
- Published by American Medical Association (AMA) in JAMA
- Vol. 323 (20), 2089-2090
- https://doi.org/10.1001/jama.2020.6771
Abstract
Since December 2019, a pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally.1 A spectrum of disease severity has been reported, with main symptoms that include fever, fatigue, dry cough, myalgia, and dyspnea. Previous strains of coronavirus have been demonstrated to invade the central nervous system through the olfactory neuroepithelium and propagate from within the olfactory bulb.2 Furthermore, nasal epithelial cells display the highest expression of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2, in the respiratory tree.3Keywords
This publication has 4 references indexed in Scilit:
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