Physical Activity and Cardiovascular Health
Top Cited Papers
- 17 August 2010
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 122 (7), 743-752
- https://doi.org/10.1161/circulationaha.109.914721
Abstract
In 1953, Morris et al1,2 published the findings from a study showing that bus conductors in London, who spent their working hours walking the length of the buses as well as climbing up and down the stairs of the English double-decker buses to collect fares, experienced half the coronary heart disease (CHD) mortality rates of their driver counterparts, who spent their day sitting behind the wheel. Investigators hypothesized that it was the physical activity of work that protected the conductors from developing CHD, at the same time realizing that other factors may also play a role because the conductors were smaller in size, as evidenced by their smaller uniform sizes. Thus was born the field of “physical activity epidemiology”: formal epidemiological investigations into the associations of physical activity with many health outcomes.4 Since the initial observations of Morris et al, many other studies have been conducted, yielding similar results: Active people have lower rates of CHD and cardiovascular disease (CVD) than inactive ones.5–7 These findings have been supported by plausible biological mechanisms, which are detailed in other articles in this review series. The collective body of evidence led the American Heart Association in 1992 to recognize physical inactivity as a risk factor for CHD and CVD8 and led the Surgeon General in 1996 to conclude that “regular physical activity or cardiorespiratory fitness decreases the risk of CVD … and CHD.”9 The basis for these conclusions was derived primarily from studies in men and in white populations; for example, in a 1990 meta-analysis of physical activity in the prevention of CHD10 that included 33 studies, women were subjects in 5 studies, and racial/ethnic minorities were the focus of 2 studies. In 2008, the federal government issued its first-ever physical activity guidelines for Americans11 based …Keywords
This publication has 84 references indexed in Scilit:
- Combined impact of lifestyle factors on mortality: prospective cohort study in US womenBMJ, 2008
- Physical Activity in the United States Measured by AccelerometerMedicine & Science in Sports & Exercise, 2008
- Cardiorespiratory Fitness and Adiposity as Mortality Predictors in Older AdultsJama-Journal Of The American Medical Association, 2007
- Physical Activity and Reduced Risk of Cardiovascular EventsCirculation, 2007
- The Obesity Epidemic in the United States Gender, Age, Socioeconomic, Racial/Ethnic, and Geographic Characteristics: A Systematic Review and Meta-Regression AnalysisEpidemiologic Reviews, 2007
- Walking decreased risk of cardiovascular disease mortality in older adults with diabetesJournal of Clinical Epidemiology, 2007
- Sedentary Behavior, Physical Activity, and the Metabolic Syndrome among U.S. AdultsObesity Research, 2005
- Walking Compared with Vigorous Exercise for the Prevention of Cardiovascular Events in WomenNew England Journal of Medicine, 2002
- Body mass index, physical inactivity and low level of physical fitness as determinants of all-cause and cardiovascular disease mortality—16 y follow-up of middle-aged and elderly men and womenInternational Journal of Obesity, 2000
- Changes in physical activity, mortality, and incidence of coronary heart disease in older menThe Lancet, 1998