Living supramolecular polymerization realized through a biomimetic approach
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- 2 February 2014
- journal article
- Published by Springer Science and Business Media LLC in Nature Chemistry
- Vol. 6 (3), 188-195
- https://doi.org/10.1038/nchem.1849
Abstract
Various conventional reactions in polymer chemistry have been translated to the supramolecular domain, yet it has remained challenging to devise living supramolecular polymerization. To achieve this, self-organization occurring far from thermodynamic equilibrium--ubiquitously observed in nature--must take place. Prion infection is one example that can be observed in biological systems. Here, we present an 'artificial infection' process in which porphyrin-based monomers assemble into nanoparticles, and are then converted into nanofibres in the presence of an aliquot of the nanofibre, which acts as a 'pathogen'. We have investigated the assembly phenomenon using isodesmic and cooperative models and found that it occurs through a delicate interplay of these two aggregation pathways. Using this understanding of the mechanism taking place, we have designed a living supramolecular polymerization of the porphyrin-based monomers. Despite the fact that the polymerization is non-covalent, the reaction kinetics are analogous to that of conventional chain growth polymerization, and the supramolecular polymers were synthesized with controlled length and narrow polydispersity.Keywords
This publication has 49 references indexed in Scilit:
- Functional Supramolecular PolymersScience, 2012
- Dendron-Mediated Self-Assembly, Disassembly, and Self-Organization of Complex SystemsChemical Reviews, 2009
- Supramolecular PolymerizationChemical Reviews, 2009
- Self-assembled π-stacks of functional dyes in solution: structural and thermodynamic featuresChemical Society Reviews, 2008
- Organogels as scaffolds for excitation energy transfer and light harvestingChemical Society Reviews, 2008
- Graphenes as Potential Material for ElectronicsChemical Reviews, 2007
- Molecular Materials by Self‐Assembly of Porphyrins, Phthalocyanines, and PerylenesAdvanced Materials, 2006
- About Supramolecular Assemblies of π-Conjugated SystemsChemical Reviews, 2005
- Supramolecular PolymersChemical Reviews, 2001
- Comparisons of Indefinite Self-Association ModelsChemical Reviews, 1996