Antioxidant activities of tocopherols on Fe2+‐ascorbate‐induced lipid peroxidation in lecithin liposomes
- 1 July 1982
- Vol. 17 (7), 511-513
- https://doi.org/10.1007/bf02535334
Abstract
The antioxidant activities of 4 tocopherols, tocol, and a water-soluble model analog of α-tocopherol were compared. Egg lecithin liposomes were used and oxidation was catalyzed by Fe2+-ascorbate. The activities decreased in the order α->β->γ->δ-tocopherol>tocol, in agreement with their potencies in vivo. The water-soluble analog was the least effective. Activity depended on the molar ratio of antioxidant to unsaturated lipid, with one molecule each of the α-, β-, γ-, δ-tocopherol and tocol capable of protecting, respectively, 220, 120, 100, 30 and 20 molecules of polyunsaturated fatty acid. The mechanism of possible antioxidant effect of the compounds used is discussed.This publication has 16 references indexed in Scilit:
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