Systematic review of the Sugarbaker procedure for pseudomyxoma peritonei
- 31 January 2005
- journal article
- review article
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 92 (2), 153-158
- https://doi.org/10.1002/bjs.4862
Abstract
Background: Pseudomyxoma peritonei, a rare progressive disease process within the peritoneum, is characterized by an abundance of mucinous fluid; if left untreated, the condition is fatal. The aim of this article is to assess the clinical effectiveness and costs of the Sugarbaker procedure for pseudomyxoma peritonei. Methods: A systematic review of the literature up to April 2004 was undertaken, with modelling of costs. Results: Five retrospective case-series reports met the inclusion criteria. Survival after operation was approximately 95 per cent at 2 years and 60–68 per cent at 10 years, with 41–52 per cent of patients having no evidence of disease at the end of follow-up. A Monte Carlo simulation model estimated the marginal cost for one patient over a maximum of 5 years to be about £ 9700 (standard deviation £ 1300). Conclusion: Evidence of the effectiveness of the Sugarbaker procedure for pseudomyxoma peritonei is limited in quantity and quality, but suggests there may be some benefit for patients. The marginal cost of the operation is about £ 9700, provided that trained and experienced staff are available to perform the procedure.Keywords
Funding Information
- UK National Health Service R&D Health Technology Assessment Programme (02/14/01)
This publication has 13 references indexed in Scilit:
- Clinical effectiveness and costs of the Sugarbaker procedure for the treatment of pseudomyxoma peritoneiHealth Technology Assessment, 2004
- Pseudomyxoma peritonei: a review of 62 casesEuropean Journal of Surgical Oncology, 2003
- Patients with pseudomyxoma peritonei associated with disseminated peritoneal adenomucinosis have a significantly more favorable prognosis than patients with peritoneal mucinous carcinomatosisCancer, 2001
- Cytoreductive surgery and peri-operative intraperitoneal chemotherapy as a curative approach to pseudomyxoma peritonei syndromeEuropean Journal of Surgical Oncology, 2001
- Pseudomyxoma Peritonei: A Review of Current LiteratureGynecologic and Obstetric Investigation, 2001
- Clinical presentation of the pseudomyxoma peritonei syndromeBritish Journal of Surgery, 2000
- Handling Uncertainty in Cost-Effectiveness ModelsPharmacoEconomics, 2000
- Disseminated Peritoneal Adenomucinosis: A Critical ReviewAnnals of Surgical Oncology, 1999
- Pseudomyxoma peritoneiBritish Journal of Surgery, 1998
- Pseudomyxoma Peritonei A Cancer Whose Biology Is Characterized by a Redistribution PhenomenonAnnals of Surgery, 1994