Remote control of cellular behaviour with magnetic nanoparticles
Top Cited Papers
- 1 March 2008
- journal article
- Published by Springer Science and Business Media LLC in Nature Nanotechnology
- Vol. 3 (3), 139-143
- https://doi.org/10.1038/nnano.2008.39
Abstract
By binding magnetic nanoparticles to the surface of cells, it is possible to manipulate and control cell function with an external magnetic field. The technique of activating cells with magnetic nanoparticles offers a means to isolate and explore cellular mechanics and ion channel activation to gain better understanding of these processes. Here, we go beyond using this technique as an investigative tool and focus on its potential to actively control cellular functions and processes with an eye towards biological and clinical applications. In particular, we focus on applications in tissue engineering and regenerative medicine.Keywords
This publication has 37 references indexed in Scilit:
- Effective cell-seeding technique using magnetite nanoparticles and magnetic force onto decellularized blood vessels for vascular tissue engineeringJournal of Bioscience and Bioengineering, 2007
- Cell Spreading and Focal Adhesion Dynamics Are Regulated by Spacing of Integrin LigandsBiophysical Journal, 2007
- The differentiation of mesenchymal stem cells by mechanical stress or/and co-culture systemBiochemical and Biophysical Research Communications, 2007
- Principles and Design of a Novel Magnetic Force Mechanical Conditioning Bioreactor for Tissue Engineering, Stem Cell Conditioning, and Dynamic In Vitro ScreeningIEEE Transactions on Nanobioscience, 2006
- Novel Methodology for Fabrication of Tissue-Engineered Tubular Constructs Using Magnetite Nanoparticles and Magnetic ForceTissue Engineering, 2005
- Calcium-channel activation and matrix protein upregulation in bone cells in response to mechanical strainJournal of Cellular Biochemistry, 2000
- Mechanical manipulation of bone and cartilage cells with ‘optical tweezers’FEBS Letters, 1999
- Mechanical Stimulation of Tissue Repair in the Hydraulic Bone ChamberJournal of Bone and Mineral Research, 1997
- Probing transmembrane mechanical coupling and cytomechanics using magnetic twisting cytometryBiochemistry and Cell Biology, 1995
- Cytoplasmic motions, rheology, and structure probed by a novel magnetic particle method.The Journal of cell biology, 1985