Antibiotic Irrigations A Plea for Controlled Clinical Trials
- 8 July 1985
- journal article
- clinical trial
- Published by Wiley in Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
- Vol. 5 (4), 222-227
- https://doi.org/10.1002/j.1875-9114.1985.tb03420.x
Abstract
Although the medical literature describes the perioperative use of antibiotic irrigations in abdominal, pelvic, orthopedic and vascular surgery, the lack of well-designed and executed, controlled clinical studies often precludes a definitive assessment of the value of this technique. Future randomized, double-blind, controlled clinical trials are required to establish its merit. In this age of cost consciousness, lavages with antibiotic solutions cannot at present be regarded as conventional medical therapy.Keywords
This publication has 48 references indexed in Scilit:
- Intraoperative Antibiotic Irrigation as Prophylaxis in Abdominal Hysterectomy: A Preliminary ReportSouthern Medical Journal, 1984
- Management of Perforated Appendicitis in Children The Controversy ContinuesAnnals of Surgery, 1983
- Use of Instillation-Suction Technique in Treatment of Chronic OsteomyelitisActa Orthopaedica, 1983
- Clinical Pharmacology of Intravenous and Intraperitoneal Aminoglycoside Antibiotics in the Prevention of Wound InfectionsAnnals of Surgery, 1978
- Irrigation of the peritoneal cavity for appendicitis in children: A double-blind studyJournal of Pediatric Surgery, 1976
- Tuberculosis of the HipClinical Orthopaedics and Related Research, 1975
- A controlled trial of intraperitoneal cephaloridineadministration in peritonitisJournal of Pediatric Surgery, 1975
- Treatment of Chronic Osteomyelitis with Emphasis on Closed Suction-Irrigation TechnicClinical Orthopaedics and Related Research, 1973
- Treatment of Chronic Osteomyelitis with the Continuous Irrigation-Suction MethodActa Orthopaedica, 1972
- KANAMYCIN AS AN INTESTINAL ANTISEPTIC AND IN THE TREATMENT OF PERITONITIS: RESUME OF CLINICAL EXPERIENCE*Annals of the New York Academy of Sciences, 1966