A potent small-molecule inducer of chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells
- 12 July 2012
- journal article
- Published by Royal Society of Chemistry (RSC) in Chemical Science
- Vol. 3 (10), 3071-3075
- https://doi.org/10.1039/c2sc20362f
Abstract
We discovered a novel small-molecule modulator 5{i,2} that can specifically induce the chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells (hBM-MSCs). Based on our biochemical and histological studies, 5{i,2} showed more of a directed differentiation of MSCs to chondrocyte balls compared to TGF-β3.This publication has 26 references indexed in Scilit:
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