Marked inflammation in catastrophic longitudinal myelitis associated with systemic lupus erythematosus
- 1 October 2007
- journal article
- case report
- Published by SAGE Publications in Lupus
- Vol. 16 (10), 823-826
- https://doi.org/10.1177/0961203307081846
Abstract
Catastrophic longitudinal myelitis is an extremely rare neurologic manifestation of collagen vascular disease, described heretofore in 11 cases of SLE and 1 of Sjogren's Syndrome. This report documents markedly abnormal and worsening CSF findings on sequential CSF examinations over a period of three days (WBC >1500 cells/μL, >80% neutrophils, markedly elevated protein, and extremely low glucose levels) in the absence of infection. These abnormalities cleared rapidly with institution of immunosuppressive therapy so that a third CSF exam done within three days revealed almost complete normalization of CSF values. These findings suggest that in some cases of CLM a strong inflammatory component may be present, while in others, other pathogenic factors may predominate. Lupus (2007) 16, 823—826.This publication has 8 references indexed in Scilit:
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