Studies on the metabolism of semen. 6. Role of hormones. Effect of castration, hypophysectomy and diabetes. Relation between blood glucose and seminal fructose

Abstract

Semen and male accessory organs were collected from rabbits and analyzed. Castration and hypophysectomy resulted in the disappearance of fructose and citric acid. These reappeared on injn. of testosterone; also of gonadotrophin in the hypophysectomized rabbit. In castrated rats, there was a direct relationship between response of accessory organs in producing fructose and citric acid and amt. of testosterone injd. The fructose content of semen increased in alloxan-diabetic rabbits and was decreased by insulin. There was a relationship between hyperglycemia and fructose level.