One-step synthesis of a cortisol derivative for radioiodination and application of the 125I-labeled cortisol to radioimmunoassay.
- 1 January 1987
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 35 (12), 5000-5003
- https://doi.org/10.1248/cpb.35.5000
Abstract
A one-step synthesis of a cortisol derivative for radioiodination is presented. The radioimmunoassay for cortisol using the bridge heterologous 125I-labeled antigen was more sensitive than that using a bridge homologous antigen. Cortisol levels in saliva and serum were easily determined by direct radioimmunoassay with the proposed 125I-labeled antigen.This publication has 11 references indexed in Scilit:
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