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Lessons From and Cautions About Noninferiority and Equivalence Randomized Trials
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Publications
Lessons From and Cautions About Noninferiority and Equivalence Randomized Trials
Lessons From and Cautions About Noninferiority and Equivalence Randomized Trials
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Peter C. Gøtzsche
Peter C. Gøtzsche
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8 March 2006
journal article
editorial
Published by
American Medical Association (AMA)
in
JAMA
Vol. 295
(10)
,
1172-1174
https://doi.org/10.1001/jama.295.10.1172
Abstract
The design of the classic, parallel-group randomized trial involves formulating a null hypothesis of no difference between 2 interventions and identifying a cli
Keywords
NONINFERIORITY
PRESPECIFIED
INTERVENTIONS
HOPE
WORSE
SEEKS
CAUTIONS
SIDED
NATURE1
SIMILARLY
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Cited by 84 articles