Patterns of Gene Transcript Abundance in the Blood of Children with Severe or Uncomplicated Dengue Highlight Differences in Disease Evolution and Host Response to Dengue Virus Infection
Open Access
- 15 February 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 199 (4), 537-546
- https://doi.org/10.1086/596507
Abstract
DNA microarrays and specific reverse-transcription polymerase chain reaction assays were used to reveal transcriptional patterns in the blood of childKeywords
This publication has 28 references indexed in Scilit:
- Differences in Global Gene Expression in Peripheral Blood Mononuclear Cells Indicate a Significant Role of the Innate Responses in Progression of Dengue Fever but Not Dengue Hemorrhagic FeverThe Journal of Infectious Diseases, 2008
- Transcriptional Activation of Interferon-Stimulated Genes but Not of Cytokine Genes after Primary Infection of Rhesus Macaques with Dengue Virus Type 1Clinical and Vaccine Immunology, 2007
- Dengue Virus Inhibits Alpha Interferon Signaling by Reducing STAT2 ExpressionJournal of Virology, 2005
- Interferon-Dependent Immunity Is Essential for Resistance to Primary Dengue Virus Infection in Mice, Whereas T- and B-Cell-Dependent Immunity Are Less CriticalJournal of Virology, 2004
- Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic feverNature Medicine, 2003
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodMethods, 2001
- Strong HLA Class I–Restricted T Cell Responses in Dengue Hemorrhagic Fever: A Double‐Edged Sword?The Journal of Infectious Diseases, 2001
- Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease SeverityThe Journal of Infectious Diseases, 2000
- Early CD69 Expression on Peripheral Blood Lymphocytes from Children with Dengue Hemorrhagic FeverThe Journal of Infectious Diseases, 1999
- Early Immune Activation in Acute Dengue Illness Is Related to Development of Plasma Leakage and Disease SeverityThe Journal of Infectious Diseases, 1999