Metabolic markers and ALT cutoff level for diagnosing nonalcoholic fatty liver disease: a community-based cross-sectional study
- 14 February 2012
- journal article
- research article
- Published by Springer Science and Business Media LLC in The Esophagus
- Vol. 47 (6), 696-703
- https://doi.org/10.1007/s00535-012-0534-y
Abstract
Untreated nonalcoholic fatty liver disease (NAFLD) may progress to liver cirrhosis or failure and is associated with the development of hepatocellular carcinoma, diabetes, and cardiovascular disease. It is therefore essential to diagnose and treat NAFLD at an early stage. To assist in this effort, this retrospective study explored the risk factors for NAFLD, and derived new surrogates, a revised alanine aminotransferase (ALT) cutoff level and a novel NAFLD index, to identify previously undiagnosed cases of NAFLD.This publication has 30 references indexed in Scilit:
- Prevalence, gender, ethnic variations, and prognosis of NASHThe Esophagus, 2010
- Ultrasound Diagnosis of Fatty Liver in Patients With Chronic Liver DiseaseJournal of Clinical Gastroenterology, 2007
- Diabetes and liver disease: An ominous associationNutrition, Metabolism and Cardiovascular Diseases, 2006
- Nonalcoholic steatohepatitis: cirrhosis, hepatocellular carcinoma, and burnt-out NASHThe Esophagus, 2004
- Normal serum aminotransferase concentration and risk of mortality from liver diseases: prospective cohort studyBMJ, 2004
- Increase in the prevalence of fatty liver in Japan over the past 12 years: analysis of clinical backgroundThe Esophagus, 2003
- Diagnosis of fatty liver diseaseEuropean Journal of Gastroenterology & Hepatology, 2003
- Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndromeHepatology, 2003
- Evaluation of Abnormal Liver-Enzyme Results in Asymptomatic PatientsNew England Journal of Medicine, 2000
- Ultrasonographical Diagnosis of Fatty Liver: Significance of the Liver-Kidney ContrastThe Tohoku Journal of Experimental Medicine, 1983