The neuronal composition of area 17 of rat visual cortex. III. Numerical considerations
- 15 August 1985
- journal article
- Published by Wiley in Journal of Comparative Neurology
- Vol. 238 (3), 263-274
- https://doi.org/10.1002/cne.902380303
Abstract
The neuronal population of area 17 of rat visual cortex has been examined by using tissue from brains fixed by perfusion. The tissue was osmicated and embedded in plastic so that the same neurons could be examined by both light and electron microscopy. In these preparations area 17 was 1.49 mm thick and by stereological procedures it was calculated that there are about 120,000 neurons beneath 1 mm2 of cortical surface. If one assumes area 17 in each hemisphere of the rat to occupy between 7.1 and 9.4 mm2 of cortical surface, then in each hemisphere the area contains between 850,000 and 1,128,000 neurons. Of these neurons 85% are pyramidal cells and 15% are nonpyramidal cells. About one‐third of the nonpyramidal cells occur in layers I and VIb, both of which contain only this kind of neuron. The remaining two‐thirds of the nonpyramidal cells are in layers II‐VIa. Within these layers it has been possible to differentiate bipolar cells from other types of nonpyramidal cells and in each of these two nonpyramidal cell groups to recognize both small and large neurons. The greatest concentration of nonpyramidal cells occurs in layer II/III. To confirm the validity of the stereologically derived data direct counts were made of the medium and large pyramidal cells in layer V.Keywords
This publication has 25 references indexed in Scilit:
- Vasoactive intestinal polypeptide-immunoreactive neurons in rat visual cortexNeuroscience, 1984
- Retinotopic organization of striate and extrastriate visual cortex in the hooded ratBrain Research, 1983
- The number of neurons in the different laminae of the binocular and monocular regions of area 17 in the catJournal of Comparative Neurology, 1983
- Cholinergic neurons in the rat cerebral cortex demonstrated by immunohistochemical localization of choline acetyltransferaseNeuroscience Letters, 1983
- Organization and morphological characteristics of cholonergic neurons: an immunocytochemical study with a monoclonal antibody to choline acetyltransferaseBrain Research, 1983
- Effects of aging and chronic arterial hypertension on the cell populations in the neocortex and archicortex of the ratActa Neuropathologica, 1982
- The forms of non‐pyramidal neurons in the visual cortex of the ratJournal of Comparative Neurology, 1978
- A new procedure for examining Golgi impregnated neurons by light and electron microscopyJournal of Neurocytology, 1977
- Connections of the cerebral cortex. I. The albino rat. A. Topography of the cortical areasJournal of Comparative Neurology, 1946
- Estimation of nuclear population from microtome sectionsThe Anatomical Record, 1946