Tests of the helix dipole model for stabilization of α-helices
- 1 April 1987
- journal article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 326 (6113), 563-567
- https://doi.org/10.1038/326563a0
Abstract
Charged groups play a critical role in the stability of the helix formed by the isolated C-peptide (residues 1-13 of ribonuclease A) in aqueous solution. One charged-group effect may arise from interactions between charged residues at either end of the helix and the helix dipole. We report here that studies of C-peptide analogues support the helix dipole model, and provide further evidence for the importance of electrostatic interactions not included in the Zimm-Bragg model for alpha-helix formation.This publication has 27 references indexed in Scilit:
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