A new pyrazolo pyrimidine derivative inhibitor of cyclooxygenase-2 with anti-angiogenic activity
- 19 March 2004
- journal article
- Published by Elsevier BV in European Journal of Pharmacology
- Vol. 488 (1-3), 225-230
- https://doi.org/10.1016/j.ejphar.2004.02.015
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Cyclooxygenase‐2 is induced in the endothelial cells throughout the central nervous system during carrageenan‐induced hind paw inflammation; its possible role in hyperalgesiaJournal of Neurochemistry, 2003
- Selective inhibitors of cyclo‐oxygenase‐2 (COX‐2) induce hypoalgesia in a rat paw model of inflammationBritish Journal of Pharmacology, 2002
- Hyperalgesia and Edema Responses Induced by Rat Peripheral Blood Mononuclear Cells Incubated with CarrageeninInflammation, 2001
- Role of Cyclooxygenases in AngiogenesisCurrent Medicinal Chemistry, 2000
- Cyclo‐oxygenase‐2 enhances basic fibroblast growth factor‐induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implantsBritish Journal of Pharmacology, 2000
- The role of platelet activating factor and other lipid mediators in inflammatory angiogenesisBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1998
- Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.JCI Insight, 1996
- COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex.Proceedings of the National Academy of Sciences of the United States of America, 1996
- Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.JCI Insight, 1994
- Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blueBiochimica et Biophysica Acta (BBA) - General Subjects, 1986