Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging
Open Access
- 11 December 2009
- journal article
- Published by Elsevier BV in American Journal of Human Genetics
- Vol. 85 (6), 823-832
- https://doi.org/10.1016/j.ajhg.2009.10.028
Abstract
No abstract availableThis publication has 51 references indexed in Scilit:
- Short telomeres are a risk factor for idiopathic pulmonary fibrosisProceedings of the National Academy of Sciences of the United States of America, 2008
- Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesisThe EMBO Journal, 2007
- Telomere length is paternally inherited and is associated with parental lifespanProceedings of the National Academy of Sciences of the United States of America, 2007
- Short Telomeres Limit Tumor Progression In Vivo by Inducing SenescenceCancer Cell, 2007
- Adult-onset pulmonary fibrosis caused by mutations in telomeraseProceedings of the National Academy of Sciences of the United States of America, 2007
- Aging of the Immune System: How Much Can the Adaptive Immune System Adapt?Immunity, 2006
- A DNA damage checkpoint response in telomere-initiated senescenceNature, 2003
- Disease states associated with telomerase deficiency appear earlier in mice with short telomeresThe EMBO Journal, 1999
- Hypervariable ultra-long telomeres in miceNature, 1990
- Telomeres shorten during ageing of human fibroblastsNature, 1990