Prevalence of Prehypertension in Mexico and Its Association With Hypomagnesemia
Open Access
- 23 January 2015
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Hypertension
- Vol. 28 (8), 1024-1030
- https://doi.org/10.1093/ajh/hpu293
Abstract
Prehypertension (preHTN) increases the risk of developing hypertension. The objectives of this study were to estimate the prevalence of preHTN in the Mexican adult population and evaluate the association between hypomagnesemia and preHTN. This study was a 2-phase, population-based study. In the first phase, 4,272 Mexican adults (aged 20–65 years) were enrolled to determine the prevalence of preHTN. In the second phase, a cross-sectional analysis was performed to evaluate the association between hypomagnesemia and preHTN. The exclusion criteria were chronic diarrhea, malignancy, hepatic and renal diseases, chronic inflammatory disease, and the intake of magnesium supplements. PreHTN was defined as a systolic blood pressure (BP) of 120–139mm Hg and/or diastolic BP of 80–89mm Hg, and hypomagnesemia was defined as a serum magnesium concentration P < 0.0005). A multiple logistic regression analysis (adjusted for age, sex, smoking, body mass index, waist circumference, fasting glucose, total cholesterol, high-density lipoprotein cholesterol, and triglycerides levels) indicated a significant association between hypomagnesemia and preHTN (odds ratio = 1.78; 95% CI: 1.5–4.0, P < 0.0005). The prevalence of preHTN in the Mexican population is 37.5%, and hypomagnesemia is strongly associated with preHTN.Keywords
This publication has 36 references indexed in Scilit:
- Hypomagnesemia and prehypertension in otherwise healthy individualsEuropean Journal of Internal Medicine, 2014
- Cardio-metabolic risk factors and prehypertension in persons without diabetes, hypertension, and cardiovascular diseaseBMC Public Health, 2013
- Association of Aldosterone and Cortisol with Cardiovascular Risk Factors in Prehypertension StageInternational Journal of Hypertension, 2012
- Metabolic characteristics of prehypertension: role of classification criteria and genderJournal of Hypertension, 2009
- Prevalence of prehypertension and hypertension and associated risk factors among Turkish adults: Trabzon Hypertension StudyJournal of Public Health, 2008
- Dietary Phosphorus and Blood PressureHypertension, 2008
- Risk of Progression to Hypertension in a Low-Income Mexican Population With Prehypertension and Normal Blood PressureAmerican Journal of Hypertension, 2007
- Moderate Weight Loss Reduces Renin and Aldosterone but does not Influence Basal or Stimulated Pituitary-adrenal Axis FunctionHormone and Metabolic Research, 2007
- Dietary Magnesium Intake and Risk of Incident Hypertension Among Middle-Aged and Older US Women in a 10-Year Follow-Up StudyThe American Journal of Cardiology, 2006
- Prevalence of Heart Disease and Stroke Risk Factors in Persons With Prehypertension in the United States, 1999-2000Archives of Internal Medicine, 2004