CT and MR Imaging of Primary Cardiac Malignancies
- 1 November 1999
- journal article
- review article
- Published by Radiological Society of North America (RSNA) in RadioGraphics
- Vol. 19 (6), 1421-1434
- https://doi.org/10.1148/radiographics.19.6.g99no031421
Abstract
Primary cardiac malignancies are rare tumors that are difficult to diagnose clinically. Different primary cardiac malignancies may have different clinical, morphologic, and radiologic features and intracardiac locations. Angiosarcoma is the most common primary cardiac malignancy. It tends to occur in the right atrium and involve the pericardium. Because of its tendency to hemorrhage, angiosarcoma often demonstrates areas of increased signal intensity with T1-weighted sequences. Undifferentiated sarcomas typically occur in the left atrium and have variable epidemiologic and radiologic features. Rhabdomyosarcoma is the most common primary cardiac malignancy in children and is more likely than other primary cardiac sarcomas to involve the valves. Primary cardiac osteogenic sarcoma almost always occurs in the left atrium and frequently demonstrates calcification. Certain features (eg, broad base of attachment, origin at a site other than the atrial septum) help differentiate this tumor from left atrial myxoma. Leiomyosarcoma favors the left atrium and tends to invade the pulmonary veins and mitral valve. Fibrosarcoma also tends to occur in the left atrium and is often necrotic. Liposarcoma is very rare and usually manifests as a large, infiltrating mass. Foci of macroscopic fat are occasionally seen. Primary cardiac lymphoma occurs more commonly in immunocompromised patients, frequently involves the pericardium, and, unlike other primary cardiac malignancies, may respond to chemotherapy. The advent of cross-sectional imaging has allowed earlier detection of primary cardiac malignancies as well as more accurate diagnosis and characterization.Keywords
This publication has 80 references indexed in Scilit:
- Brain metastasis from myxofibrosarcoma of the heartActa Neurochirurgica, 1997
- Primary pericardial sarcomaAmerican Heart Journal, 1994
- Sunray appearance on enhanced magnetic resonance image of cardiac angiosarcoma with pericardial obliterationAmerican Heart Journal, 1994
- Primary Angiosarcoma of the Heart. Report of a Case and Review of the Literature.Japanese Heart Journal, 1993
- Primary cardiac rhabdomyosarcoma exhibiting transient and pronounced regression with chemotherapyAmerican Heart Journal, 1990
- Angiosarcoma of the heart: Three-year survival and follow-up by nuclear magnetic resonance imagingAmerican Heart Journal, 1988
- Intracardiac undifferentiated sarcoma in infancyJournal of the American College of Cardiology, 1985
- Fibrosarcoma of the right ventricle — a case reportInternational Journal of Cardiology, 1985
- Primary osteosarcoma of the heartAmerican Heart Journal, 1985
- A Case of Primary Heart Sarcoma with Acute Cardiac TamponadeJapanese Heart Journal, 1967