Design by necessity
- 1 February 2000
- journal article
- editorial
- Published by Springer Science and Business Media LLC in Nature
- Vol. 403 (6770), 606-607
- https://doi.org/10.1038/35001176
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Directed evolution of new catalytic activity using the α/β-barrel scaffoldNature, 2000
- Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylationNature, 1999
- Rapid evolution of a protein in vitro by DNA shufflingNature, 1994
- On the origin of enzymatic speciesTrends in Biochemical Sciences, 1993
- Stepwise improvements in catalytic effectiveness: independence and interdependence in combinations of point mutations of a sluggish triosephosphate isomeraseBiochemistry, 1991
- De Novo Design, Expression, and Characterization of Felix: a Four-Helix Bundle Protein of Native-Like SequenceScience, 1990
- The evolution of α/β barrel enzymesTrends in Biochemical Sciences, 1990
- Characterization of a Helical Protein Designed from First PrinciplesScience, 1988
- Role of arginine-292 in the substrate specificity of aspartate aminotransferase as examined by site-directed mutagenesisBiochemistry, 1988
- Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5Å resolution: using amino acid sequence dataNature, 1975