Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease
Top Cited Papers
Open Access
- 28 March 2014
- journal article
- review article
- Published by Wiley in British Journal of Pharmacology
- Vol. 171 (8), 1890-1906
- https://doi.org/10.1111/bph.12516
Abstract
Mitochondria are no longer considered to be solely the static powerhouses of the cell. While they are undoubtedly essential to sustaining life and meeting the energy requirements of the cell through oxidative phosphorylation, they are now regarded as highly dynamic organelles with multiple functions, playing key roles in cell survival and death. In this review, we discuss the emerging role of mitochondrial fusion and fission proteins, as novel therapeutic targets for treating a wide range of cardiovascular diseases. Linked ArticlesThis article is part of a themed issue on Mitochondrial Pharmacology: Energy, Injury & Beyond. To view the other articles in this issue visitKeywords
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