High Resolution Spatio-Temporal EEG-MEG Analysis of Rolandic Spikes
Open Access
- 1 March 2004
- journal article
- clinical trial
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal Of Clinical Neurophysiology
- Vol. 21 (2), 84-95
- https://doi.org/10.1097/00004691-200403000-00002
Abstract
Using high resolution EEG and MEG and a realistic volume conductor model, the authors investigated spatio-temporal aspects of the sources of spikes in children with benign rolandic epilepsy. A 64-channel EEG and simultaneous 151-channel MEG of interictal spike activity in five children all having general and/or focal seizures were recorded. A spatio-temporal multiple signal classification (MUSIC) analysis was performed on the spike data. Sources having a complex spatio-temporal configuration as well as single stationary sources were found. Results for the EEG and MEG were different. In this group of five patients, both high resolution EEG and MEG revealed that in some cases sources well separated in space and time exist, whereas in other cases only single source activity can be resolved. For multiple sources, differences for EEG and MEG in timing and localization of activity suggest that sources are spatio-temporally distributed. Sources can propagate from initial activity in the finger/hand area around the central sulcus down to the mouth/tongue area.Keywords
This publication has 10 references indexed in Scilit:
- Measurement of the Conductivity of Skull, Temporarily Removed During Epilepsy SurgeryBrain Topography, 2003
- The Existence of Two Sources in Rolandic Epilepsy: Confirmation with High Resolution EEG, MEG and fMRIBrain Topography, 2001
- The conductivity of the human skull: results of in vivo and in vitro measurementsIEEE Transactions on Biomedical Engineering, 2000
- A new method for myocardial activation imagingIEEE Transactions on Biomedical Engineering, 1997
- Localization of the motor hand area to a knob on the precentral gyrus. A new landmarkBrain, 1997
- Dipole source analysis of rolandic spikes in benign rolandic epilepsy and other clinical syndromesBrain Topography, 1993
- Sequential EEG mapping may differentiate “epileptic” from “non-epileptic” rolandic spikesElectroencephalography and Clinical Neurophysiology, 1992
- Multiple dipole modeling and localization from spatio-temporal MEG dataIEEE Transactions on Biomedical Engineering, 1992
- Source parameter estimation in inhomogeneous volume conductors of arbitrary shapeIEEE Transactions on Biomedical Engineering, 1989
- Stability of source estimates in rolandic spikesBrain Topography, 1989