Nosocomial Infections With Ceftazidime-Resistant Pseudomonas aeruginosa: Risk Factors and Outcome

Abstract
Prospective studies were conducted for nosocomialPseudomonas aeruginosainfections from February 1, 1994, to October 30,1995. Of 97P aeruginosaisolates from 97 patients, 35 were resistant to ceftazidime. Logistic regression revealed previous cephalosporin or piperacillin use as independent risk factors for nosocomial ceftazidime-resistantP aeruginosainfection. Pulsed-field gel electrophoresis revealed that four nosocomial ceftazidime-resistantP aeruginosainfections were caused by cross-infection, probably through medical personnel.