Alternative Explanation of Stiffening in Cross-Linked Semiflexible Networks
- 18 October 2005
- journal article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 95 (17), 178102
- https://doi.org/10.1103/physrevlett.95.178102
Abstract
Strain stiffening of filamentous protein networks is explored by means of a finite strain analysis of a two-dimensional network model of cross-linked semiflexible filaments. The results show that stiffening is caused by nonaffine network rearrangements that govern a transition from a bending-dominated response at small strains to a stretching-dominated response at large strains. Filament undulations, which are key in the existing explanation of stiffening, merely postpone the transition.Keywords
This publication has 20 references indexed in Scilit:
- Elastic Behavior of Cross-Linked and Bundled Actin NetworksScience, 2004
- The Bimodal Role of Filamin in Controlling the Architecture and Mechanics of F-actin NetworksJournal of Biological Chemistry, 2004
- Strain Hardening of Actin Filament NetworksJournal of Biological Chemistry, 2000
- Keratin Filament Suspensions Show Unique Micromechanical PropertiesJournal of Biological Chemistry, 1999
- Mechanical Effects of Neurofilament Cross-bridgesJournal of Biological Chemistry, 1996
- Elasticity of Semiflexible Biopolymer NetworksPhysical Review Letters, 1995
- Probing transmembrane mechanical coupling and cytomechanics using magnetic twisting cytometryBiochemistry and Cell Biology, 1995
- Viscoelastic properties of vimentin compared with other filamentous biopolymer networks.The Journal of cell biology, 1991
- Strain enhancement of elastic modulus in fine fibrin clotsThrombosis Research, 1988
- Rheology of Fibrin Clots. VI. Stress Relaxation, Creep, and Differential Dynamic Modulus of Fine Clots in Large Shearing DeformationsJournal of Rheology, 1983