Deciphering the Spike Train of a Sensory Neuron: Counts and Temporal Patterns in the Rat Whisker Pathway
Open Access
- 6 September 2006
- journal article
- Published by Society for Neuroscience in Journal of Neuroscience
- Vol. 26 (36), 9216-9226
- https://doi.org/10.1523/jneurosci.1491-06.2006
Abstract
Rats achieve remarkable texture discriminations by sweeping their facial whiskers along surfaces. This work explores how neurons at two levels of the sensory pathway, trigeminal ganglion and barrel cortex, carry information about such stimuli. We identified two biologically plausible coding mechanisms, spike counts and patterns, and used “mutual information” to quantify how reliably neurons in anesthetized rats reported texture when “decoded” according to these candidate mechanisms. For discriminations between surfaces of different coarseness, spike counts could be decoded reliably and rapidly (within 30 ms after stimulus onset in cortex). Information increased as responses were considered as spike patterns with progressively finer temporal precision. At highest temporal resolution (spike sequences across six bins of 4 ms), the quantity of “information” in patterns rose 150% for ganglion neurons and 110% for cortical neurons above that in spike counts. In some cases, patterns permitted discriminations not supported by spike counts alone.Keywords
This publication has 43 references indexed in Scilit:
- Texture Signals in Whisker VibrationsJournal of Neurophysiology, 2006
- Data-Robust Tight Lower Bounds to the Information Carried by Spike Times of a Neuronal PopulationNeural Computation, 2005
- Neural codes for perceptual discrimination in primary somatosensory cortexNature Neuroscience, 2005
- Synergy, Redundancy, and Independence in Population Codes, RevisitedJournal of Neuroscience, 2005
- Neuronal Encoding of Texture in the Whisker Sensory PathwayPLoS Biology, 2005
- Current Flow in Vibrissa Motor Cortex Can Phase-Lock With Exploratory Rhythmic Whisking in RatJournal of Neurophysiology, 2004
- Role of Spike Timing in the Forelimb Somatosensory Cortex of the RatJournal of Neuroscience, 2004
- Whisker Vibration Information Carried by Rat Barrel Cortex NeuronsJournal of Neuroscience, 2004
- First spikes in ensembles of human tactile afferents code complex spatial fingertip eventsNature Neuroscience, 2004
- Population Coding of Stimulus Location in Rat Somatosensory CortexNeuron, 2001